A ICSI with single embryo transfer.

This is the Correct Answer

[Feedback :- This increases the risk of monochorionic monoamniotic (MCMA) twins fivefold; the reasons for this are poorly understood.]

B Ovulation induction.

[Feedback :- More likely to result in dizygotic twins.]

C Natural conception.

[Feedback :- Natural conception is more likely to result in dizygotic twins (60%). 40% are monozygotic, and of all monozygotic (MZ) twins 63% are monochorionic diamniotic (MCDA), 33% are dichorionic diamniotic (DCDA) with either separate or fused placentas, and only 4% are monochorionic monoamniotic (MCMA).]

D Family history of multiple pregnancy in sister.

[Feedback :- Family history of multiple pregnancy is most likely due to multiple ovulation and therefore more likely to result in DCDA twins.]

E Maternal age 35–39 years.

[Feedback :- This is more likely to result in dizygotic twins for reasons that are poorly understood, and is independent of assisted reproductive technologies.]